Addiction

Abstract Objective The crisis of opioid use puts a strain on resources in the United States and worldwide. There are 3 US Food and Drug Administration–approved medications for treatment of opioid use disorder: methadone, buprenorphine, and...

Key Points Question What treatments for cocaine use disorder are associated with objective reductions in cocaine use among adults? Findings In this meta-analysis of 157 clinical trials comprising 402 treatment groups and 15 842 participants...

Cocaine is an addictive stimulant drug that originates from the leaves of the coca plant, which is indigenous to South America. The drug's effects include heightened alertness, attention, and energy, as well as feelings of euphoria and...

Introduction The markets for hexahydrocannabinol (HHC) and related semi-synthetic cannabinoids (SSC) are rapidly evolving areas with relatively limited information currently available. The European situation presented in Section 1 can only...

Objective: To better understand current developments in the treatment of stimulant use. Background: Stimulant drugs are second only to cannabis as the most widely used class of illicit drug globally, accounting for 68 million past-year...

It has been widely reported that youth alcohol consumption has decreased over recent years. What is the evidence to support this view? What are the implications for alcohol related health harm, promotion of safe drinking and health policy...