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The Situation of Homelessness and Substance Use in India and the Impact of COVID-19 Pandemic
Ecolink Alumnis honor Global Trainers on Intl Women's Day
Ecolink Alumnis honor global trainers as outstanding Women of the Year on Women’s day.
Mangalore, India: Ecolink Alumni Association with over 200 students from 18 countries honored its Master trainers who trained over 250 addiction...
Integrating Tobacco Use Disorder Interventions in Addiction Treatment: A guide for addiction treatment clinicians and programs
Background
Between 65-87% of patients in addiction treatment smoke tobacco, compared to about 21% of the general population. These high rates of tobacco use contribute to significant patient suffering and early death. Over 53% of people...
An observational prospective cohort study of naloxone use at witnessed overdoses, Kazakhstan, Kyrgyzstan, Tajikistan, Ukraine
Abstract
Objective
To determine whether participation in the United Nations Office on Drugs and Crime (UNODC) and the World Health Organization’s (WHO) Stop Overdose Safely (S-O-S) take-home naloxone training project in Kazakhstan...
Factors associated with retention on medications for opioid use disorder among a cohort of adults seeking treatment in the community
Abstract
Background
Medication treatment for opioid use disorder (OUD) (MOUD; buprenorphine and methadone) reduces opioid use and overdose. Discontinuation of MOUD can quickly lead to relapse, overdose and death. Few persons who...
Sex Trafficking and Substance Use Identifying High-Priority Needs Within the Criminal Justice System
Substance use disorder (SUD) is common among victims of sex trafficking. Traffickers may exploit individuals' existing opioid use or other SUDs to coerce them into sex trafficking, or they may facilitate substance use to keep trafficking...
Diagnostic Utility of New Short Versions of AUDIT to Detect Binge Drinking in Undergraduate Students
Abstract
This study examines the usefulness of two AUDIT adaptations with a sample of 907 undergraduate alcohol users. On the one hand, it includes the AR2i that encompasses revised A2r and A3r consumption items, and on the other hand—in...
The Role of Age of Onset in Problematic Alcohol Consumption: Artefact or Cohort Effect?
Abstract
Age of onset has been reported as a crucial predictor for alcohol consumption in adolescence. However, several authors have warned against it as an unreliable artefact accounted by the tendency to delay age of onset as...
Associations of Alcohol Consumption and Smoking With Disease Risk and Neurodegeneration in Individuals With Multiple Sclerosis in the United Kingdom
Abstract
Importance Understanding the effects of modifiable risk factors on risk for multiple sclerosis (MS) and associated neurodegeneration is important to guide clinical counselling.
Objective To investigate associations of...
Effect of Combination Treatment With Varenicline and Nicotine Patch on Smoking Cessation Among Smokers Who Drink Heavily A Randomized Clinical Trial
Abstract
Importance The concurrent use of both tobacco and alcohol causes substantial disease and early mortality, and smokers who drink heavily tend to be less successful in smoking cessation than smokers who do not. Although...
Final Evaluation Report of Capacity Building for Effective Implementation of UPC Core Course in NDDCB Preventive Staff, Sri Lanka
People with tobacco use disorder exhibit more prefrontal activity during preparatory control but reduced anterior cingulate activity during reactive control
Abstract
Reduced inhibitory control and a hypersensitivity to reward are key deficits in drug dependents; however, they tend to be studied in isolation. Here, we seek to understand the neural processes underlying control over reward and...
Long-term consequences of alcohol use in early adolescent mice: Focus on neuroadaptations in GR, CRF and BDNF
Abstract
Our aim was to assess the cognitive and emotional state, as well as related-changes in the glucocorticoid receptor (GR), the corticotropin-releasing factor (CRF) and the brain-derived neurotrophic factor (BDNF) expression of...
The relationship between craving and insular morphometry in regular cocaine users: Does sex matter?
Abstract
While it has been suggested that cocaine use and relapse in women is more strongly related to stress-relief craving, whereas cocaine use in men is more strongly related to reward craving, the neural mechanisms that underlie...
Anomalies in global network connectivity associated with early recovery from alcohol dependence: A network transcranial magnetic stimulation and electroencephalography study
Abstract
Although previous research in alcohol dependent populations identified alterations within local structures of the addiction ‘reward’ circuitry, there is limited research into global features of this network, especially in early...
Alcohol-related stimuli modulate functional connectivity during response inhibition in young binge drinkers
Abstract
Binge drinking is a pattern of intermittent excessive alcohol consumption that is highly prevalent in young people. Neurocognitive dual-process models have described substance abuse and adolescence risk behaviours as the result...
Effects of family history of substance use disorder on reward processing in adolescents with and without attention-deficit/hyperactivity disorder
Abstract
Patients with attention-deficit/hyperactivity disorder (ADHD) often develop early onset substance use disorder (SUD) and show poor treatment outcomes. Both disorders show similar reward-processing alterations, but it is unclear...