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Cognition and Impulsivity in Adults with ADHD with and without Cocaine and/or Crack Dependence
Background: Substance use disorder (SUD) is a common comorbidity in adults with Attention Deficit Hyperactivity Disorder (ADHD). However, there have been few studies on cognitive profiles of these patients. Impulsivity is also commonly...
Gender Differences in Substance Use and Psychiatric Distress among Medical Students
ABSTRACT
Background: Medical student wellness has emerged as an important issue in medical education. The purpose of the present study was to obtain a comprehensive assessment of substance use, psychological distress, and help-seeking...
Identification of Novel Signal Transduction, Immune Function, and Oxidative Stress Genes and Pathways by Topiramate for Treatment of Methamphetamine Dependence Based on Secondary Outcomes
Background: Topiramate (TPM) is suggested to be a promising medication for treatment of methamphetamine (METH) dependence, but the molecular basis remains to be elucidated.
Methods: Among 140 METH-dependent participants randomly assigned...
Gender and Age Effects on the Trajectory of Depression in Opioid Users during Methadone Maintenance Treatment
Introduction: Both heroin use and depression are significant health problems. Methadone maintenance treatment (MMT) can be of great benefit to heroin users. However, changes in the level of depression in heroin users during MMT are not...
Getting to Zero Alcohol-Impaired Driving Fatalities: A Comprehensive Approach to a Persistent Problem
Alcohol-impaired driving remains the deadliest and costliest danger on U.S. roads today. Every day in the United States, 29 people die in an alcohol-impaired driving crash—one death every 49 minutes. After decades of progress, alcohol...
Effect of Exercise versus Cognitive Behavioural Therapy or no Intervention on Anxiety, Depression, Fitness and Quality of Life in Adults with Previous Methamphetamine Dependency
Abstract
Background
Methamphetamine (MA) is a highly addictive psychostimulant used by approximately 52 million people worldwide. Chronic MA abuse leads to detrimental physiological and neurological changes, as well as increases in...
Granulocyte-Colony Stimulating Factor Controls Neural and Behavioral Plasticity in Response to Cocaine
Cocaine addiction is characterized by dysfunction in reward-related brain circuits, leading to maladaptive motivation to seek and take the drug. There are currently no clinically available pharmacotherapies to treat cocaine addiction...
Contribution of Smoking to Socioeconomic Inequalities in Mortality
Abstract
Background: Smoking contributes to socioeconomic inequalities in mortality, but the extent to which this contribution has changed over time and driven widening or narrowing inequalities in total mortality remains unknown. We...
Effectiveness Bank Matrix Cell: Engaging Organisations, Engaging Treatment
Key studies on the how the functioning of treatment organisations affects the implementation and impacts of improvements. Introduces two high-quality, evidence-based US quality improvement resources, and asks what makes a treatment service...
Altered Parietal Activation during Non-symbolic Number Comparison in Children with Prenatal Alcohol Exposure
Number processing is a cognitive domain particularly sensitive to prenatal alcohol exposure, which relies on intact parietal functioning. Alcohol-related alterations in brain activation have been found in the parietal lobe during symbolic...
Reductions in Corpus Callosum Volume Partially Mediate Effects of Prenatal Alcohol Exposure on IQ
Disproportionate volume reductions in the basal ganglia, corpus callosum (CC) and hippocampus have been reported in children with prenatal alcohol exposure (PAE). However, few studies have investigated these reductions in high prevalence...
Effects of Acute Alcohol Intoxication on Empathic Neural Responses for Pain
The questions whether and how empathy for pain can be modulated by acute alcohol intoxication in the non-dependent population remain unanswered. To address these questions, a double-blind, placebo-controlled, within-subject study design was...
Feasibility and Fit of an Evidence-Based Universal Prevention Program Adapted for Youth Involved in the Justice System
Amanda Kerry, Claire V Crooks
Introduction: Over one-third of Canadian youth have engaged in some form of delinquent behavior by the age of 14 (Savoie, 2006). In the United States, approximately 31 million youth are under juvenile court...
Feasibility of Implementing a Culturally Adapted Parenting Intervention for Karen Refugee Caretakers in the U.S.
Elizabeth A Wieling, Jaime Ballard, Christopher Mehus, Damir Utrzan
Introduction: Increasing numbers of children are fleeing to the United States after exposure to war and conflict. Children exposed to war have high rates of negative...
Implementing the KiVa Bullying Prevention Programme in the UK
Suzy Clarkson, Judy Hutchings
KiVa is a Finnish anti-bullying programme, developed at Turku University. It is based on robust research by the programme developer, Christina Salmivalli, that shows how the responses of bystanders maintain or...
Improving Outcomes for Adolescents at High-Risk of Poor Social, Economic and Health Outcomes
Anthony Shakeshaft
Introduction: Adolescents exposed to multiple, co-occurring risk factors experience disproportionately high rates of harm, and Indigenous adolescents are over-represented in this population. Despite this, little is known...
Development of a Smartphone App-Based Messaging Intervention to Encourage HIV Self-Testing in Hefei, China
Cui Yang, Ashley Perez, Don Operario, Hongo Zhang, Nickolas Zaller
Introduction: Research in China has found that MSM avoid HIV testing at clinics or public health departments due in part to stigma and fear of disclosure of their MSM...
Piloting a Universal Violence Prevention Programme in Jamaican Grade One Primary Schools
Marsha Bowers, Helen Baker-Henningham, Yakeisha Scott
Introduction: Corporal punishment is a widely used behaviour management strategy in Jamaican schools and exposure to corporal punishment at school is associated with poor child mental...
The Impact of an Indigenous Led, Community-Based Trial to Reduce Alcohol Related Harms in New South Wales, Australia
Mieke Snijder
Introduction: Indigenous people of Australia experience a higher burden of health-related harm compared to non-Aboriginal Australians, which is most starkly evidenced by the Aboriginal life expectancy being an estimated 10...